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  • Title: Calcium phosphate biomaterials as bone drug delivery systems: a review.
    Author: Verron E, Khairoun I, Guicheux J, Bouler JM.
    Journal: Drug Discov Today; 2010 Jul; 15(13-14):547-52. PubMed ID: 20546919.
    Abstract:
    A short review is proposed on the existing literature for the research performed in calcium phosphate (CaP) biomaterials used as drug delivery systems. In the first part, a brief update is given on the performance of both CaP ceramics and CaP cements. Second, a review of the research and clinical situation is developed for CaP materials already used as drug delivery systems. Experimental works performed for local delivery are reported. In particular, a description is given of the in vitro and in vivo studies in which these materials are loaded with various proteins and drugs.
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