These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Metal-organic frameworks as efficient heterogeneous catalysts for the regioselective ring opening of epoxides.
    Author: Dhakshinamoorthy A, Alvaro M, Garcia H.
    Journal: Chemistry; 2010 Jul 26; 16(28):8530-6. PubMed ID: 20549723.
    Abstract:
    An iron-based metal-organic framework, [Fe(BTC)] (BTC: 1,3,5-benzenetricarboxylate) is an efficient catalyst in the ring opening of styrene oxide with alcohols and aniline under mild reaction conditions. Out of the various alcohols tested for ring opening of styrene oxide, methanol was found to be the most reactive in terms of percentage conversion and reactivity. The rate of the ring-opening reaction of styrene oxide decreases as the size of the alcohol is increased, suggesting the location of active sites in micropores. [Fe(BTC)] was a truly heterogeneous catalyst and could be reused without loss of activity. The analogous compound [Cu(3)(BTC)(2)] was also found to be effective, although with somewhat lower activity than [Fe(BTC)]. The present heterogeneous protocol is compared with a homogeneous catalyst to give an insight into the reaction mechanism.
    [Abstract] [Full Text] [Related] [New Search]