These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Perineurial cell ensheathement of muscle fibers: a new syndrome of fatigable muscle weakness mimicking myasthenia gravis.
    Author: Michaelis ML, King JA, Leech RW, Min KW, Brumback RA.
    Journal: Clin Neuropathol; 1991; 10(2):79-84. PubMed ID: 2054981.
    Abstract:
    Many newly discovered pathological and physiological variants of neuromuscular junction function have been identified. We report a case of a myasthenia gravis-like syndrome with onset of ptosis at age six years and eventual evaluation for peripheral weakness twenty years later. Subsequent muscle biopsy showed a previously unreported finding of perineurial cell ensheathement of the muscle fibers. We suggest that the ensheathement of the muscle cells by perineurial cells may alter the microenvironment interfering with neuromuscular transmission.
    [Abstract] [Full Text] [Related] [New Search]