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  • Title: [Erythropoiesis and osteogenesis (I. The interaction of the reparative processes of bone and hematopoietic tissues)].
    Author: Filimonov VI, Nedospasov VO, Stepanova NV.
    Journal: Fiziol Zh (1978); 1991; 37(2):12-8. PubMed ID: 2055322.
    Abstract:
    The dynamics of erythropoiesis during the bone restoration and under the conditions of perturbing influence: fracture and hemolytic anemia have been studied in the experiment. It is found that under the conditions of callus formation the process of proliferation and differentiation of red cells in the bone marrow is inhibited. The observed effect of erythropoiesis inhibition may be caused by the intercellular interaction of regenerating tissues in their "struggle" for microphages, which, while being the centre of the erythroid insula secure the maturation of erythroid precursors, and at the same time they can take part in the bone formation process.
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