These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A new cytotoxic 1-azaanthraquinone from the stems of Goniothalamus laoticus.
    Author: Tip-pyang S, Limpipatwattana Y, Khumkratok S, Siripong P, Sichaem J.
    Journal: Fitoterapia; 2010 Oct; 81(7):894-6. PubMed ID: 20554005.
    Abstract:
    A new 1-azaanthraquinone, named laoticuzanone A (1), and a synthetically known 3-methyl-1H-1-azaanthracene-2,9,10-trione (2), together with four known compounds, Griffithazanone A (3), methyl sinapate (4), methyl p-coumarate (5), and p-hydroxyphenylethyl p-coumarate (6) were isolated from the stems of Goniothalamus laoticus. Their structures were established on the basis of spectroscopic data as well as comparisons with the previous literature data. Compound 1 showed the highest cytotoxicity against KB and HeLa cells with IC(50) values of 0.68 and 0.50 μg/ml, respectively.
    [Abstract] [Full Text] [Related] [New Search]