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  • Title: Transclival cerebrospinal fluid rhinorrhea as the initial presenting symptom of a tiny intradural chordoma.
    Author: Feng K, Qiuhang Z, Qiuyi Q.
    Journal: J Clin Neurosci; 2010 Aug; 17(8):1083-5. PubMed ID: 20554205.
    Abstract:
    We report a patient with a tiny intradural clival chordoma, which was identified following presentation with cerebrospinal fluid (CSF) rhinorrhea as the initial symptom. The transclival dural defect and the intradural tumor were successfully localized by both radiological investigation and intraoperative endoscopic inspection. The tumor was totally resected and the CSF fistula was repaired by an endoscopic endonasal approach. The diagnosis, possible mechanisms and management of this rare condition are discussed. The role of endoscopy in identifying and treating the clival CSF rhinorrhea is emphasized. To our knowledge, this is the first report of a clival fistula secondary to a tiny intradural chordoma.
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