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  • Title: [CT-guided radiofrequency ablation of non-small cell lung cancer].
    Author: Camacho Romero J, Oliver Goldaracena JM, Rodríguez Caravaca G, Hernando Polo S, Martel Villagrán J, Trapero M.
    Journal: Med Clin (Barc); 2010 Nov 06; 135(13):581-5. PubMed ID: 20557907.
    Abstract:
    UNLABELLED: FUNDAMENTAL AND OBJECTIVE: To present the first experiences with a series of consecutive cases of patients with non-small cell lung cancer (NSCLC) treated with radiofrequency ablation (RFA), considering its clinical applicability, effectiveness and safety. PATIENTS AND METHODS: Descriptive study performed from June 2003 to March 2009, with a series of consecutive cases of patients with NSCLC treated with RFA, selected according to well-defined inclusion criteria, in different stages of the disease. The variables studied were local recurrence, complications, staging, demographic and procedure-related variables. Local control was assessed in posterior controls according to CT morphology criteria and/or lesion enhancement after intravenous contrast. Survival curves were estimated. Statistical analysis was performed with SPSS version 15.0 application. RESULTS: We studied 15 patients (46-88 years), diagnosed with NSCLC in different stages, in a total of 22 sessions. After 1 year of follow up, 75% of lesions showed no local recurrence (15). The progression-free survival and disease-free survival in localized stage at one year were 81,3% and 75% respectively. In 8 of 22 sessions there were post-procedure complications (36.36%). Of all complications (14), 28.5% were pneumothorax, 21.4% alveolar hemorrhage and 7.1% pulmonary infarction. CONCLUSION: ARF is clinically useful in the treatment of patients with inoperable NSCLC, considering the high percentage of local control and few major complications, being thus a plausible, effective and safe therapeutic alternative.
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