These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Platinum-catalyzed formal Markownikoff's hydroamination/hydroarylation cascade of terminal alkynes assisted by tethered hydroxyl groups.
    Author: Patil NT, Kavthe RD, Raut VS, Reddy VV.
    Journal: J Org Chem; 2009 Aug 21; 74(16):6315-8. PubMed ID: 20560573.
    Abstract:
    An efficient method for Markownikoff's hydroamination-hydroarylation of alkynols using PtBr(2) as catalyst has been developed. The platinum-catalyzed reactions of alkynols with amino group containing aromatics were achieved in methanol over a reaction time of 6-24 h and temperature ranging from rt to 80 degrees C. This method works well for a variety of alkynols and aromatic amino compounds to give substituted pyrrolo[1,2-a]quinoxalines and indolo[3,2-c]quinolines in good to excellent yields.
    [Abstract] [Full Text] [Related] [New Search]