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  • Title: [Effect of a direct electric current on modification of bone and ligament repair processes--experimental investigation of a rabbit model].
    Author: Akai M, Wadano Y, Yabuki T, Oda H, Sirasaki Y, Tateishi T.
    Journal: Nihon Seikeigeka Gakkai Zasshi; 1991 Apr; 65(4):196-206. PubMed ID: 2056235.
    Abstract:
    Investigations of the effect of direct current on 1) fracture healing, and 2) ligament healing was conducted by applying 10 microA to 1) the defect of the fibula, and 2) that of the patellar ligament of adult rabbits. After time periods for stimulation all specimens were tested with combinations of roentgenological, histological, biomechanical and biochemical methods. The results were analyzed and compared with the non-stimulated, opposite side and with the normal tissue. The electricity produced 1) a more massive callus with normal histological features in an early stages at the fracture site, and 2) higher tensile stiffness and earlier change of the collagen types in the newly-formed tissue, though no significant differences were observed as to 1) the mechanical parameters of callus and bone material, and 2) histological findings of repairing tissue. Electrical stimulation was indicated not only on bone tissue but also on non-osseous tissues and their components.
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