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Title: Mesenteric lymph node cavitation syndrome. Author: Freeman HJ. Journal: World J Gastroenterol; 2010 Jun 28; 16(24):2991-3. PubMed ID: 20572301. Abstract: The mesenteric lymph node cavitation syndrome consists of central necrosis of mesenteric lymph nodes and may occur with either celiac disease or a sprue-like intestinal disease that fails to respond to a gluten-free diet. Splenic hypofunction may also be present. The cause is not known but its development during the clinical course of celiac disease is usually indicative of a poor prognosis for the intestinal disorder, a potential for significant complications including sepsis and malignancy, particularly T-cell lymphoma, and significant mortality. Modern abdominal imaging modalities may permit earlier detection in celiac disease so that earlier diagnosis and improved understanding of its pathogenesis may result.[Abstract] [Full Text] [Related] [New Search]