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  • Title: [Paravalvular leak following surgical valve replacement: is there a role for percutaneous paravalvular leak reduction?].
    Author: Noble S, lbrahim R, Basmadjian A, Müller H, Lerch R, Roffi M.
    Journal: Rev Med Suisse; 2010 Jun 02; 6(251):1154-8. PubMed ID: 20572360.
    Abstract:
    After valve replacement, significant paravalvular leaks (PVL) may develop in up to 12.5% of the cases. Signs and symptoms include congestive heart failure and/or haemolysis and therefore may require reintervention. Redo valve surgery is considered the therapy of choice for symptomatic patients, either by valve replacement or leak repair. Considering the risk of morbidity and mortality associated with a surgical reintervention and the high post-surgical recurrence of PVL, the endovascular treatment represents an attractive alternative to surgery for high risk patients. The percutaneous approach aims at PVL reduction by implantation of certain occluder devices. The procedure is technically feasible in 60 to 90% of the cases according to different series. Technical success is associated with clinical improvement in 50 to 80% of the cases.
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