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  • Title: Behavioural abnormalities in children with nephrotic syndrome--an underappreciated complication of a standard treatment?
    Author: Neuhaus TJ, Langlois V, Licht C.
    Journal: Nephrol Dial Transplant; 2010 Aug; 25(8):2397-9. PubMed ID: 20573807.
    Abstract:
    Behaviour and psychosocial adjustment are impaired in children with steroid-sensitive idiopathic nephrotic syndrome (SSNS). Both illness-related variables and family climate play a role. Steroid treatment-both short- and long-term-is an important contributor among other determinants. The exact mechanisms by which steroids lead to behavioural alterations in humans is unclear. Optimizing the benefit/risk ratio of steroid treatment in children with SSNS is a constant goal.
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