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  • Title: Enantioselective synthesis of highly functionalised amides by copper-catalysed vinylogous Mukaiyama aldol reaction.
    Author: Frings M, Goedert D, Bolm C.
    Journal: Chem Commun (Camb); 2010 Aug 14; 46(30):5497-9. PubMed ID: 20574579.
    Abstract:
    Amides with quaternary stereogenic centers have been synthesised by catalytic asymmetric vinylogous Mukaiyama aldol reactions. The chiral copper-sulfoximine catalyst gives rise to products with moderate to good yields and up to 92% ee.
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