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  • Title: Combination of cytomegalovirus enhancer with human cellular promoters for gene-induced chondrogenesis of human bone marrow mesenchymal stem cells.
    Author: Iwai R, Kumagai Y, Fujiwara M, Wakitani S, Takagi M.
    Journal: J Biosci Bioeng; 2010 Nov; 110(5):593-6. PubMed ID: 20576467.
    Abstract:
    High-expression plasmid vectors for human mesenchymal stem cells (MSCs) were constructed by combination of cytomegalovirus immediate-early enhancer with cellular promoters. MSCs transfected with the vector showed higher transgene production of a cytokine, which increased the differentiation level to chondrocytes.
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