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  • Title: Bilateral orbital bone infarction in sickle-cell disease.
    Author: Ghafouri RH, Lee I, Freitag SK, Pira TN.
    Journal: Ophthalmic Plast Reconstr Surg; 2011; 27(2):e26-7. PubMed ID: 20577135.
    Abstract:
    This is a case of a 2-year-old boy with sickle cell disease who presented with bilateral eyelid swelling, limited extraocular motility, and lateral subperiosteal fluid collection associated with bilateral lateral orbital wall infarctions on MRI. The patient was managed medically with intravenous fluids, analgesics, broad-spectrum antibiotics, systemic steroids, and clinically improved. Patients with sickle cell disease are susceptible to infarction of the orbital bones during vaso-occlusive crises. Orbital wall infarction can lead to acute proptosis and restricted extraocular motility. Orbital wall infarction should be considered in sickle cell patients with orbital diseases so that appropriate treatment can be instituted promptly to prevent the serious sequelae of orbital compression syndrome.
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