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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Suppression of melatonin secretion in healthy subjects with eyeglass LED delivery system.
    Author: Claustrat B, Brun J, Borson-Chazot F, Cohen-Tannoudji D, Claustrat F, Julien J, Lemoine P.
    Journal: Neuro Endocrinol Lett; 2010; 31(3):330-5. PubMed ID: 20588229.
    Abstract:
    OBJECTIVE: Practicability remains a problem in light therapy of biological rhythm disorders. We report here the effect on melatonin secretion of a device consisting of a prototype of eyeglasses including light emitting diodes (LED) in lenses (Somnavue). METHODS: Light (1,200 lx) was administered in a randomised crossover design to ten healthy subjects with Somnavue for 1 or 2 hours, Lumino (a helmet which administers light) for 1 hour, and placebo, beginning at 01:00 h. Plasma melatonin concentrations were evaluated between 20:00-05:00 h. RESULTS: Multiple comparisons showed differences between placebo and Somnavue administered for one or two hours (p<0.01 and p<0.05 respectively) and Lumino and placebo (p<0.05). CONCLUSIONS: In conclusion, Somnavue was able to suppress melatonin. The development of such a device could increase adherence with light treatment in SAD or circadian rhythm sleep disorders.
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