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Title: alpha and beta-adrenoceptors in chicken airways. Author: Chand N, Eyre P. Journal: Res Commun Chem Pathol Pharmacol; 1978 Feb; 19(2):353-9. PubMed ID: 205928. Abstract: Isolated chicken bronchus (which had been partially contracted to carbachol) relaxes to isoproterenol and epinephrine but contracts weakly to phenylephrine. Propranolol (a beta-adrenoceptor blocker) antagonizes isoproterenol and reverses epinephrine-induced relaxations to feeble contractions. Phenylephrine-induced bronchoconstrictions and constrictions to epinephrine (in the presence of beta-blockade) were blocked by phentolamine. The results of this study showed the predominance of beta-)inhibitory) adrenoceptors and some alpha-(excitatory) adrenoceptors in the bronchus of the adult domestic fowl.[Abstract] [Full Text] [Related] [New Search]