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  • Title: Trigoxyphins A-G: diterpenes from Trigonostemon xyphophylloides.
    Author: Lin BD, Han ML, Ji YC, Chen HD, Yang SP, Zhang S, Geng MY, Yue JM.
    Journal: J Nat Prod; 2010 Jul 23; 73(7):1301-5. PubMed ID: 20593838.
    Abstract:
    Six new oxygenated daphnane-type diterpenoids, trigoxyphins A-F (1-6), a phenanthrene-type diterpenoid, trigoxyphin G (7), and two known compounds were isolated from twigs of Trigonostemon xyphophylloides. Their structures were established using spectroscopic methods. Compounds 1 and 2 exhibited strong cytotoxic activity against HL60 (IC(50): 0.27 and 0.49 microM) and A549 (IC(50): 7.5 and 4.9 microM) tumor cell lines, respectively.
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