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  • Title: [Gastroprotective properties of mexidol and hypoxen].
    Author: Novikov VE, Kriukova NO, Novikov AS.
    Journal: Eksp Klin Farmakol; 2010 May; 73(5):15-8. PubMed ID: 20597364.
    Abstract:
    Experimental damage in the stomach mucosa of test rats was modeled by acetylsalicylic acid (aspirin-induced ulcerogenesis). The number of ulcers and the total area of erosive injury in the mucous membrane were studied. Prophylactic treatment with mexidol and hypoxen in a daily dose of 50 mg/kg reduces the aspirin-induced damage of stomach mucosa. The gastroprotective properties of drugs are probably related to their antioxidant and antihypoxant effects.
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