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  • Title: Cardiac amyloidosis: an approach to diagnosis and management.
    Author: Halwani O, Delgado DH.
    Journal: Expert Rev Cardiovasc Ther; 2010 Jul; 8(7):1007-13. PubMed ID: 20602561.
    Abstract:
    Cardiac amyloidosis is a myocardial disease characterized by extracellular amyloid infiltration throughout the heart. Cardiac amyloidosis has a wide spectrum of clinical manifestations but the most frequent presentation is heart failure. Differential diagnoses from other restrictive cardiomyopathies is important. A combination of clinical, electrocardiographic and imaging methods is commonly used to diagnose this disease. Definite diagnosis is based on endomyocardial biopsy and treatment of cardiac amyloidosis is a challenge. Heart transplantation, although controversial, has demonstrated survival benefit.
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