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  • Title: Secondary excision for cervical intraepithelial neoplasia: an evaluation of two treatment methods.
    Author: Bowring J, Tulloch I, Phadnis SV, Young MP, Evans H, Walker P.
    Journal: J Obstet Gynaecol; 2010; 30(5):511-4. PubMed ID: 20604658.
    Abstract:
    A small proportion of women require repeat treatments for cervical intraepithelial neoplasia (CIN). This study aimed to compare the effectiveness of two cervical excisional techniques offered within a London teaching hospital (large loop excision of the transformation zone (LLETZ) and laser cone biopsy) when carried out as secondary procedures. A significantly larger volume of tissue was excised following laser cone biopsy, however the depth of the specimen did not differ significantly. A trend for a larger percentage of secondary specimens, resulting in complete endo-cervical margins and a larger proportion of women achieving cytology negative for CIN post-treatment was shown within the laser cone biopsy group.
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