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  • Title: Effect of ampicillin and sulbactam/ampicillin on the immune system.
    Author: Gismondo MR, Chisari G, Lo Bue AM.
    Journal: J Int Med Res; 1991; 19 Suppl 1():24A-28A. PubMed ID: 2060690.
    Abstract:
    An investigation was carried out into the possible effects of ampicillin and a sulbactam/ampicillin combination on the immune system of healthy subjects. The following immunological variables were compared before and after antibiotic therapy: proliferation response of peripheral mononuclear cells to phytohaemagglutinin; variation of T- and B-lymphocytes; dosage of interleukin-2; and production of immunoglobulin A. The data obtained did not demonstrate any immunodepressive activity by either ampicillin or the sulbactam/ampicillin combination.
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