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  • Title: Clinical and pathologic features of endometrial hyperplasia, pyometra, and endometritis in cats: 79 cases (1980-1985).
    Author: Potter K, Hancock DH, Gallina AM.
    Journal: J Am Vet Med Assoc; 1991 Apr 15; 198(8):1427-31. PubMed ID: 2061164.
    Abstract:
    Records of 79 cats determined to have endometrial hyperplasia (EH) with or without pyometra or endometritis were studied. Forty-eight cats (61%) were spayed or died because of complications relating to reproductive tract disease. All other cats were free of clinical signs of disease, and lesions were found incidentally during routine ovariohysterectomy or at necropsy. Prevalence of uterine lesions was greater in cats greater than or equal to 5 years old. Breeding, age at first breeding, and queening could not be correlated with clinical or pathologic signs of disease. Seventy-one percent (34/48) of cats with clinical signs referable to the reproductive tract had histologic evidence of pyometra or endometritis, whereas only 19% (6/31) of cats without clinical signs had histologic evidence of either disease. Only 23% (9/39) of cats without pyometra or endometritis had corpora lutea (CL) in at least one ovary, whereas 40% (16/40) of cats with either pyometra or endometritis had CL. We concluded that the prevalence of EH in cats increases with age in sexually intact female cats, and that most cases of pyometra or endometritis, but not EH, in cats are associated with retained CL.
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