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  • Title: [Virilizing tumours of the adrenal cortex with unimpaired menstruation (author's transl)].
    Author: Hartemann P, Leclére J, Groussin M, Valdenaire JC, Mizrahi R.
    Journal: Ann Endocrinol (Paris); 1977; 38(6):399-400. PubMed ID: 206182.
    Abstract:
    Virilizing adenomas of the adrenal cortex entail, typically, hirsutism, amenorrhea and hypertrophy of the clitoris. We report two cases of adrenal adenoma, both revealed by hirsutism and significant biological features, but both without any alteration of the menstrual cycle. One of our 2 patients showed moderate hypertrophy of the clitoris. In the first patient, the tumour has been located thanks to dexamethasone--modifiying adrenal secretion, and in the second patient, thanks to angiography. These two cases reported are a warning never to neglect more hirsutism, even, when unobstrusive, and always to undertake minimal hormonal investigations.
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