These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Design and synthesis of a novel fluorescence probe for Zn2+ based on the spirolactam ring-opening process of rhodamine derivatives.
    Author: Sasaki H, Hanaoka K, Urano Y, Terai T, Nagano T.
    Journal: Bioorg Med Chem; 2011 Feb 01; 19(3):1072-8. PubMed ID: 20620067.
    Abstract:
    The spirolactam ring-opening process of rhodamine derivative is one of the most useful mechanisms for controlling fluorescence properties. However, the open/closed equilibrium reaction of rhodamine spirolactam has not been well characterized. Therefore, we examined the relationship between the spirolactam ring-opening process of rhodamine derivatives and the structure of the xanthene moiety. Based on the results of this investigation, we selected a candidate xanthene moiety for a Zn(2+) sensor, and successfully developed a new fluorescence probe for Zn(2+).
    [Abstract] [Full Text] [Related] [New Search]