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  • Title: Copper-mediated cross-coupling of 1,1-dibromo-1-alkenes with dialkyl phosphites: a convenient synthesis of 1-alkenylphosphonates.
    Author: Evano G, Tadiparthi K, Couty F.
    Journal: Chem Commun (Camb); 2011 Jan 07; 47(1):179-81. PubMed ID: 20625578.
    Abstract:
    An efficient and stereoselective procedure for the preparation of E-1-alkenylphosphonates by copper-mediated cross-coupling between 1,1-dibromo-1-alkenes and dialkyl phosphites is reported. The reaction allows for formal substitution of both bromine atoms, respectively, by an hydrogen and a dialkoxyphosphoryl.
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