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  • Title: [Effects of electroacupuncture of "Neiguan (PC 6) and Taichong (LR 3) on cardiac function in acute myocardial ischemia rabbits].
    Author: Cai RL, Hu L, Wang KM, Wu ZJ, Chen YN, Long DH, He L, Liu J.
    Journal: Zhen Ci Yan Jiu; 2010 Apr; 35(2):104-7, 123. PubMed ID: 20626141.
    Abstract:
    OBJECTIVE: To observe the effect of electroacupuncture (EA) of "Neiguan" (PC 6) and "Taichong" (LR 3) on mechnical activities of the heart in acute myocardial ischemia (AMI) rabbits. METHODS: Fifty chinchilla rabbits were randomized into normal control, model, EA-PC 6, EA-LR 3 and non-acupoint groups (n = 8/group). AMI model was duplicated by intravenous injection (femoral vein) of posterior pituitrin (3 U/kg). The maximal ascending velocity (+ dp/dt max), maximal descending velocity (-dp/dt max) and left ventricular systolic pressure (LVSP) of the heart were recorded by using Biopac Bio-signal system. EA (1 mA, 2 Hz) was applied to PC 6, LR 3 and non-acupoint for 10 min. RESULTS: Compared with normal control group, + dp/dt max, - dp/dt max and LVSP of the heart in model group reduced significantly (P < 0.01); while in comparison with model group, left ventricular + dp/dt max and - dp/dt max at 10 min after EA in EA-PC 6 and EA-LR 3 groups increased markedly (P < 0.01), and LVSP of EA-PC 6 group increased remarkably (P < 0.05). No significant differences were found between EA-non-acupoint group and model group in the above-mentioned 3 indexes (P > 0.05). CONCLUSION: Both EA of PC 6 and LR 3 points can improve AMI induced reduction of the left ventricular myocardial mechanical activities in the rabbit, and the therapeutic effect of EA-PC 6 is superior to that of EA-LR 3.
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