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Title: New isoprenylated flavonoids and cytotoxic constituents from Artocarpus tonkinensis. Author: Ma JP, Qiao X, Pan S, Shen H, Zhu GF, Hou AJ. Journal: J Asian Nat Prod Res; 2010 Jul; 12(7):586-92. PubMed ID: 20628938. Abstract: Two new isoprenylated flavonoids, artotonins A and B (1 and 2), along with 13 known compounds (3-15), were isolated from the roots of Artocarpus tonkinensis A. Chev. ex Gagnep. The structures were elucidated by spectroscopic methods. Cyclocommunol (6), isocyclomulberrin (7), cudraflavone C (11), and morusin (13) exhibited cytotoxicity against hepatocellular carcinoma (SMMC-7721) and gastric carcinoma (BGC-823 and SGC-7901) cell lines.[Abstract] [Full Text] [Related] [New Search]