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  • Title: Sustained protection from pentavalent rotavirus vaccination during the second year of life at a large, urban United States pediatric hospital.
    Author: Boom JA, Tate JE, Sahni LC, Rench MA, Quaye O, Mijatovic-Rustempasic S, Patel MM, Baker CJ, Parashar UD.
    Journal: Pediatr Infect Dis J; 2010 Dec; 29(12):1133-5. PubMed ID: 20634776.
    Abstract:
    Fecal specimens from children presenting to Texas Children's Hospital with acute gastroenteritis were tested for the presence of rotavirus. Children were grouped according to vaccination status, and pentavalent rotavirus vaccine effectiveness was calculated. Pentavalent rotavirus vaccine effectiveness against severe rotavirus gastroenteritis was sustained during the first 2 years of the vaccination program. Overall 3-dose effectiveness was 83% to 86%; it was 92% to 93% among children 6 to 11 months of age and 78% to 84% among children ≥12 months of age.
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