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  • Title: Neuromyelitis optica associated with subacute human T-lymphotropic virus type 1 infection.
    Author: Olindo S, Bonnan M, Merle H, Signate A, Smadja D, Cabre P.
    Journal: J Clin Neurosci; 2010 Nov; 17(11):1449-51. PubMed ID: 20638847.
    Abstract:
    Although human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy, or tropical spastic paraparesis (HAM/TSP), is usually considered as a progressive myelopathy, a subacute variant has been described. It is unusual for optic neuritis (ON) to be associated with an HTLV-1 infection. Neuromyelitis optica (NMO) is characterised by severe attacks of acute transverse myelitis and ON of unknown aetiology. We report a 61-year-old Afro-Caribbean male patient with subacute HAM/TSP associated with bilateral ON that occurred 5years previously. To our knowledge this is the first report of recurrent NMO syndrome associated with HTLV-1 infection.
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