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  • Title: Plasma acid and alkaline phosphatase in patients with breast cancer.
    Author: Nguyen M, Bonneterre J, Hecquet B, Desoize B, Demaille A.
    Journal: Anticancer Res; 1991; 11(2):831-3. PubMed ID: 2064338.
    Abstract:
    Acid and alkaline phosphatase were determined in 107 breast cancer patients to study their potential value in case of bone metastases. The patients were divided into 4 groups: A, patients without metastases (n = 34); B, metastatic patients without bone lesions (n = 37); C, patients with metastases in and outside of bones (n = 24), D, patients with bone-only metastases (n = 12). Tartrate resistant acid phosphatase (TR-ACP), and bone alkaline phosphatase (bone-ALP) were significantly higher in patients with metastases than in patients without. However, no difference in TR-ACP was observed between subgroups of metastatic patients.
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