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  • Title: Temporomandibular disorders associated with metastases to the temporomandibular joint: a review of the literature and 3 additional cases.
    Author: Kruse AL, Luebbers HT, Obwegeser JA, Edelmann L, Graetz KW.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Aug; 110(2):e21-8. PubMed ID: 20659692.
    Abstract:
    INTRODUCTION: Metastases involving the oral cavity account for 1% to 8% of all malignancies in the oral cavity Involvement of the temporomandibular joint (TMJ) is uncommon. METHOD AND RESULTS: We conducted a review of the literature between 1954 and 2008 regarding metastases to the TMJ. In total, 48 patients were found and in 28 patients a previous history of malignant neoplasm was known. The primary tumor was most commonly found in the breast (34%), followed by the lung (21%). Adenocarcinoma was predominant (72.97%). Three new patients with TMJ pain as a first symptom for a disseminated tumor are also examined here. CONCLUSION: Establishing an exact diagnosis of metastatic lesions in the TMJ can provide a diagnostic challenge. Clinicians should include the suspicion of cancer in the differential diagnosis, in particular when patients have a previous history of malignant neoplasm or do not respond to treatment appropriately.
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