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  • Title: Effects of probiotic Lactobacillus salivarius WB21 on halitosis and oral health: an open-label pilot trial.
    Author: Iwamoto T, Suzuki N, Tanabe K, Takeshita T, Hirofuji T.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Aug; 110(2):201-8. PubMed ID: 20659698.
    Abstract:
    OBJECTIVE: The objective of this study was to evaluate whether oral administration of lactobacilli alters the degree of halitosis and clinical conditions associated with halitosis. STUDY DESIGN: Twenty patients with genuine halitosis were given 2.0 x 10(9)Lactobacillus salivarius WB21 and xylitol in tablet form daily. Oral malodor and clinical parameters were evaluated at the same time of day for each patient after 2 and 4 weeks. RESULTS: All 20 patients were positive for L. salivarius DNA in their saliva at 2 weeks, although 12 patients were negative for this organism at baseline. Oral malodor parameters significantly decreased at 2 weeks in the subjects with physiologic halitosis. The scores of an organoleptic test and bleeding on probing significantly decreased at 4 weeks in the subjects with oral pathologic halitosis. CONCLUSIONS: Oral administration of probiotic lactobacilli primarily improved physiologic halitosis and also showed beneficial effects on bleeding on probing from the periodontal pocket.
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