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  • Title: Cushing syndrome in an infant due to cortisol secreting adrenal pheochromocytoma: a rare association.
    Author: Kumar M, Kumar V, Talukdar B, Mohta A, Khurana N.
    Journal: J Pediatr Endocrinol Metab; 2010 Jun; 23(6):621-5. PubMed ID: 20662337.
    Abstract:
    Adrenocortical tumors are the most common cause of endogenous Cushing syndrome in infancy and early childhood. Cushing syndrome resulting from ectopic adrenocorticotrophic hormone (ACTH) producing tumor has been infrequently reported in adults. Cortisol secreting pheochromocytoma is rarely reported in literature. We report an eleven month old child presenting to us as Cushing syndrome with hypertension due to left adrenal tumor. He was treated with antihypertensives and left adrenalectomy was done under perioperative glucocorticoid coverage. Diagnosis of pheochromocytoma was made only after histopathology. Despite the rare association of Cushing syndrome and pheochromocytoma, preoperative diagnosis of pheochromocytoma is required for appropriate perioperative medical and anaesthetic management to prevent life threatening complications.
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