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  • Title: Epidural ropivacaine versus ropivacaine plus tramadol in postoperative analgesia in children undergoing major abdominal surgery: a comparison.
    Author: Inanoglu K, Ozcengiz D, Gunes Y, Unlugenc H, Isik G.
    Journal: J Anesth; 2010 Oct; 24(5):700-4. PubMed ID: 20665055.
    Abstract:
    PURPOSE: In this study, we aimed to compare the effects of ropivacaine alone and ropivacaine plus tramadol administered epidurally for postoperative analgesia in children. METHODS: Following Ethics Committee approval and informed parent consent, 44 children aged between 2 and 12 years, with ASA physical status I or II, who were undergoing major abdominal surgery were included in the study. Following tracheal intubation, patients were placed into lateral decubitus position and an epidural catheter (22-24 G) was inserted by using a Tuohy needle. Patients were randomly divided into two groups to receive either ropivacaine alone (0.2%), 0.7 ml/kg, in group I, or ropivacaine (0.2%) plus tramadol (2 mg/kg), with total volume 0.7 ml/kg, in group II, epidurally in both groups. Hemodynamic variables, pain and sedation scores, duration of analgesia, and side effects were recorded postoperatively. RESULTS: The duration of analgesia was significantly longer in group RT than in group R (298.6 ± 28 and 867.9 ± 106.8 min in group I and II, respectively) (P < 0.05). CHEOPS scores were significantly lower in group RT at 30 min, 45 min, and 3 h postoperatively than in group R (P < 0.05). However, sedation scores were similar between the two groups. Twenty-two patients (100%) in group R and 13 patients (59%) in group RT needed supplemental analgesia postoperatively. There were no significant differences in side effects between the groups. CONCLUSION: In children undergoing major abdominal surgery, epidural tramadol, added to epidural ropivacaine, provided lower pain scores, longer duration of analgesia, and lower postoperative analgesic requirement.
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