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  • Title: Vesiculopustular eruption in a neonate with trisomy 21 syndrome as a clue of transient myeloproliferative disorders.
    Author: Piersigilli F, Diociaiuti A, Boldrini R, Auriti C, Curci M, El Hachem M, Seganti G.
    Journal: Cutis; 2010 Jun; 85(6):286-8. PubMed ID: 20666188.
    Abstract:
    We report the case of a vesiculopustular eruption associated with a transient myeloproliferative disorder (TMD) in a neonate with trisomy 21 syndrome. Examination of a skin biopsy showed a dermal mixed inflammatory infiltrate including atypical megakaryoblasts. As the white blood cell count spontaneously normalized, the eruption disappeared. This case report and review of the literature demonstrates that a vesiculopustular eruption could be an important clue to identify TMD in a neonate.
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