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  • Title: [Porphyria cutanea tarda, hemosiderosis and hepatocellular carcinoma: report of one case].
    Author: Whittle C, Hepp J, Armas R, Schultz M.
    Journal: Rev Med Chil; 2010 May; 138(5):581-5. PubMed ID: 20668813.
    Abstract:
    Porphyria cutanea tarda (PCT) is a hereditary or acquired disease. It can be unleashed by iron overload, alcohol, estrogens and other conditions. In these patients, hepatic involvement can be associated to cirrhosis, iron overload or C and B viral infections, that are predisposing factors for hepatocellular carcinoma. We report a 69-year-old man with PTC, hemosiderosis and hepatocarcinoma. The tumor was diagnosed during a routine ultrasound examination for early detection of malignant lesions. The patient was subjected to a right hepatic excision. The pathological examination of the surgical piece confirmed the diagnosis and disclosed free surgical margins. After 18 months of follow up, the patient had a relapse and a liver transplantation was performed.
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