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  • Title: Complete clinical response to neoadjuvant chemotherapy in a 54-year-old male with Askin tumor.
    Author: Mulsow J, Jeffers M, McDermott R, Geraghty J, Rothwell J.
    Journal: Thorac Cardiovasc Surg; 2010 Aug; 58(5):306-8. PubMed ID: 20680911.
    Abstract:
    Askin tumor is a tumor of the thoracopulmonary region that most commonly affects children and adolescents. These rare tumors are a form of primitive neuroectodermal tumor and typically carry a poor prognosis. Treatment is multimodal and consists of a combination of neoadjuvant chemotherapy, radical resection, and adjuvant chemo- and radiotherapy or all of the above. Surgery is advocated in most cases. We report a case of Askin tumor in a 54-year-old male who showed rapid and complete response to neoadjuvant chemotherapy. This allowed potentially radical surgery to be avoided. At one-year follow-up he remains disease-free.
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