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Title: A silicon nanowire-based electrochemical glucose biosensor with high electrocatalytic activity and sensitivity. Author: Su S, He Y, Song S, Li D, Wang L, Fan C, Lee ST. Journal: Nanoscale; 2010 Sep; 2(9):1704-7. PubMed ID: 20689869. Abstract: An electrochemical glucose biosensor was developed by immobilizing glucose oxidase (GOx) on an electrode decorated with a novel nanostructure, silicon nanowires (SiNWs) with in situ grown gold nanoparticles (AuNPs). The immobilized GOx displayed a pair of well-defined and quasi-reversible redox peaks with a formal potential (E(o ')) of -0.376 V in a phosphate buffer solution. The fabricated glucose biosensor has good electrocatalytic activity toward oxidation of glucose. In addition, such resultant SiNWs-based glucose biosensor possesses high biological affinity. Particularly, the apparent Michaelis-Mentan constant was estimated to be 0.902 mM, which is much smaller than the reported values for GOx at a range of nanomaterials-incorporated electrodes. Consequently, this novel SiNWs-based biosensor is expected to be a promising tool for biological assays (e.g., monitoring blood glucose).[Abstract] [Full Text] [Related] [New Search]