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  • Title: [Optimization of combination modes of medical materials in extract of Huanglian Jiedu decoction by semi-bionic extraction].
    Author: Dou J, Sun X, Zhang Z, Yu D, Li C.
    Journal: Zhongguo Zhong Yao Za Zhi; 2010 May; 35(10):1256-60. PubMed ID: 20707193.
    Abstract:
    OBJECTIVE: To optimize the combination modes of medical materials in extract of Huanglian Jiedu decoction. METHOD: Divided the medical materials of Huanglian Jiedu decotion into 15 groups and extracted by semi-bionic estraction (SBE), the contents of berberine, baicalin, geniposide, total alkaloid, total flavonoid, total integral calculus area of HPLC and extract of 1 000 were determined, standardized, weighted and evaluated, respectively. RESULT: The maximum evaluated value Y for the extracting technique was AD + BC. CONCLUSION: The optimal combination mode of the perscription is that Rhizoma Coptidis and Fructus Gardeniae, Radix Scutellariae and Cortex Phellodendri Amurensis are decocted together respectively then the two decoctions are merged.
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