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  • Title: Construction and regional localization of clones from a NotI linking library from human chromosome 17q.
    Author: Borrow J, Black DM, Goddard AD, Yagle MK, Frischauf AM, Solomon E.
    Journal: Genomics; 1991 Jun; 10(2):477-80. PubMed ID: 2071152.
    Abstract:
    A NotI linking library was constructed from a somatic cell hybrid containing chromosome 17q as its only human material. A total of 112 human clones were assigned to nine regions of 17q using a somatic cell hybrid mapping panel. The library includes clones that detect the acute promyelocytic leukemia and von Recklinghausen neurofibromatosis translocation breakpoints at 17q11.2-12 and 17q11.2, respectively, on pulsed-field gel electrophoresis. The mapped clones represent over 50% of the estimated number of NotI sites on 17q, and therefore constitute an important resource for long-distance mapping.
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