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  • Title: [Multiple nodular pulmonary amyloidosis complicated with Sjögren syndrome].
    Author: Sakai T, Tsushima T, Kimura D, Fukuda I, Kamata Y, Hatanaka R, Yamada Y.
    Journal: Kyobu Geka; 2010 Aug; 63(9):818-21. PubMed ID: 20715466.
    Abstract:
    A 67-year-old woman, who had been treated for Sjögren syndrome and rheumatoid arthritis for 10 years, was consulted for examination of multiple nodular pulmonary nodules. She has been pointed out multiple pulmonary nodules on chest computed tomography (CT) for 7 years, of which the number and the size gradually increased. When visuting our hospital, approximately 20 nodules up to 10 mm in size were noted. Thoracoscopic resection of the nodule was performed and histological diagnosis was amyloid, which was negative for A- and P- component and positive for transthyretin. Neither amyloid deposition in other organs nor abnormal protein in serum and urine was detected. The diagnosis of localized nodular pulmonary amyloidosis was established. As far as our knowledge, this is the 1st report of transthyretin amyloidosis with Sjögren syndrome.
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