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  • Title: [A case of Down's syndrome associated with recurrent testicular tumor treated by chemotherapy successfully: review of 41 cases in Japanese literature].
    Author: Yoneda S, Nakazawa S, Takezawa K, Kato T, Tanigawa G, Fujita K, Okumi M, Hosomi M, Fushimi H, Yamaguchi S.
    Journal: Hinyokika Kiyo; 2010 Jul; 56(7):397-401. PubMed ID: 20724816.
    Abstract:
    A 35-year-old male patient with Down' s syndrome received radical inguinal orchitectomy for left testicular tumor in 2006. Histological examination revealed a typical seminoma. 18 months after the operation, we found a metastasis in the right retroperitoneum lymph node. He received adjuvant chemotherapy (bleomycin, etoposide, and cisplatin : BEP). After 3 cycles of chemotherapy, the tumor disappeared. There is no obvious re-occurrence sign and general condition is good after chemotherapy. As we treated a relapse of seminoma in Down's syndrome successfully, we report this case and review 41 cases in Japanese literatures.
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