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  • Title: Are generic drugs really inferior medicines?
    Author: Moore N, Berdaï D, Bégaud B.
    Journal: Clin Pharmacol Ther; 2010 Sep; 88(3):302-4. PubMed ID: 20725079.
    Abstract:
    In this issue Gagne et al. report an elegant case-crossover study of seizures in patients on antiepileptic drugs. They found that a dispensation episode approximately triples the risk of having a seizure within 21 days, but the risk is not statistically different whether the dispensation was of the same brand-name or generic drug as previously used or a switch from brand-name to a generic or from a generic to a brand name. The cause of the seizure might be a delay in taking medication or late redispensation, among others, but apparently the nature of the product dispensed is not relevant in this study; this may alleviate some of the concerns about generic drugs and epilepsy.
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