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Title: [Congenital thrombocytopathies]. Author: Kirchmaier CM, Pillitteri D. Journal: Internist (Berl); 2010 Sep; 51(9):1109-14, 1116-7. PubMed ID: 20725709. Abstract: Inherited thrombocytopathies are much less frequent in comparison to acquired platelet function disorders. However, congenital disorders can lead to severe bleeding tendency and are often not diagnosed. They are induced by different platelet defects based on disorders of platelet adhesion, receptors, secretion and signal transduction. In some cases they are associated with thrombocytopenia, giant platelets and various comorbidities. This article gives an overview regarding diverse defects, their diagnosis and treatment options.[Abstract] [Full Text] [Related] [New Search]