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  • Title: Benign childhood epilepsy with centro-temporal spikes: evolutive clinical, cognitive and EEG aspects.
    Author: Tedrus GM, Fonseca LC, Castilho DP, Pacheco EM, Campregher AA, Bittar MC.
    Journal: Arq Neuropsiquiatr; 2010 Aug; 68(4):550-5. PubMed ID: 20730308.
    Abstract:
    Thirty-two children with benign childhood epilepsy with centrotemporal spikes (BECTS) were studied for a mean period of 27.6 months. The characteristics of the seizures, electroencephalogram (EEG), WISC-III and School Performance Test were compared at the start and end of the study. Nine (28.1%) children continued having seizures. Epileptiform activity (EA) on the EEG reduced in number and was no longer recorded in 6 (18.7%) children. There was a significant improvement in the performance and perceptual organization IQ values. The improvement in reading performance failed to reach statistical significance. The performance in arithmetic worsened in 43.7% of the children, and this was associated with the persistence of epileptic seizures. There were no significant correlations between changes in cognitive aspects and characteristics of EA. There is a need to continue this study, and also search for other factors influencing the evolution of cognitive abilities in children with BECTS.
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