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  • Title: Drug-induced subacute cutaneous lupus erythematosus associated with omeprazole.
    Author: Toms-Whittle LM, John LH, Buckley DA.
    Journal: Clin Exp Dermatol; 2011 Apr; 36(3):281-3. PubMed ID: 20738320.
    Abstract:
    Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly erythematous plaques in a photosensitive distribution, and the presence of anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, but occasional cases may be drug-induced or associated with a hereditary deficiency of complement components. We report two cases of drug-induced SCLE precipitated by the proton pump inhibitor, omeprazole. Drug-induced disease should be considered in all atypical or extensive cases of SCLE, especially in elderly patients.
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