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  • Title: Identification of cis-3'-hydroxycotinine as a urinary nicotine metabolite.
    Author: Voncken P, Rustemeier K, Schepers G.
    Journal: Xenobiotica; 1990 Dec; 20(12):1353-6. PubMed ID: 2075752.
    Abstract:
    1. cis-3'-Hydroxycotinine was detected as an S(-)-nicotine metabolite in the urine of smokers as well as in the urine of rats and hamsters dosed with nicotine. 2. The excreted amount of cis-3'-hydroxycotinine is lower than that of the trans-isomer.
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