These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Intracerebroventricular infusions of insulin increase vasopressin release in rats.
    Author: Nishimura M, Takahashi H, Matsusawa M, Ikegaki I, Nakanishi T, Hirabayashi M, Yoshimura M.
    Journal: Clin Exp Pharmacol Physiol; 1990 Nov; 17(11):763-8. PubMed ID: 2078904.
    Abstract:
    1. The role of cerebral insulin or insulin-like immunoreactive substance (ILI) on arginine-vasopressin (AVP) release using rats was investigated. Feeding rats with a high salt diet for 4 weeks significantly decreased the contents of ILI in both the hypothalamus and pituitary gland. Intracerebroventricular infusions of insulin (4 and 40 micrograms/min for 30 min) increased plasma AVP concentrations dose-dependently without hypoglycaemia, but decreased hypothalamic and pituitary contents of AVP. 2. These results indicate that ILI in the brain may play a role in the secretion of AVP, and that this mechanism could be operated to control a water-sodium balance.
    [Abstract] [Full Text] [Related] [New Search]