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  • Title: Chlamydia trachomatis and cervical intraepithelial neoplasia in married women in a Middle Eastern community.
    Author: Valadan M, Yarandi F, Eftekhar Z, Danvish S, Fathollahi MS, Mirsalehian A.
    Journal: East Mediterr Health J; 2010 Mar; 16(3):304-7. PubMed ID: 20795445.
    Abstract:
    The objective of this study was to determine the association between vaginal Chlamydia infection and cervical intraepithelial neoplasia (CIN). Data were collected in a case-control study for 60 patients with CIN in biopsy and 85 control subjects with normal colposcopy and biopsy. Serum antibodies to C trachomatis were associated with an increased risk for CIN [odds ratio (OR) = 7.3; 95% confidence interval (CI) 1.5-35.2)]. There was also a significant association between presence of inclusion bodies for C. trachomatis and CIN (OR = 5.5; 95% CI 2.4-12.4). These results indicate a strong association between CIN and chlamydial cervicitis.
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